New US estimates of sepsis in kids point to urgent need to reduce high mortality rates
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-Jun-2026 20:15 ET (26-Jun-2026 00:15 GMT/UTC)
Researchers from Ann & Robert H. Lurie Children’s Hospital of Chicago were among the multicenter team of experts who determined more accurate national estimates of non-neonatal pediatric sepsis using readily available clinical data from electronic health records. As they recently reported in JAMA, sepsis occurred in 1.3% of pediatric hospitalizations, with 10% mortality rate, corresponding to more than 18,000 U.S. cases and more than 1,800 deaths annually. Neither pediatric sepsis incidence nor mortality changed significantly from 2016 to 2022.
A gut-lung connection influences susceptibility to infection by Acinetobacter baumannii, a leading cause of hospital-acquired infections. Researchers found that antibiotics disrupt the gut microbiota; suppress protective immune system pathways in the lungs; and increase the severity of A. baumannii pneumonia. The findings highlight the gut microbiota as a potential therapeutic target to prevent lung infections with A. baumannii and potentially other pathogens.
Researchers have developed a new methodology that uses artificial intelligence (AI) tools to identify and count target viruses more efficiently than previous techniques. The new approach can be used in applications such as pharmaceutical biomanufacturing.
Over the years, scientific research has led to the development of several pharmacological therapies for this disease. Now, a study coordinated by the University of Trento (Italy) marks a turning point, as it identified a gene therapy for individuals with cystic fibrosis caused by a specific mutation and for whom there was no treatment available until now. They are about 10% of all those with the disease. The results open up further prospects because they could lead to a definitive cure for patients with cystic fibrosis who are currently dependent on drugs.
For centuries, the inability to regrow lost body parts has been considered a defining limitation of humans and other mammals. While animals like salamanders can regenerate entire limbs, humans are left with scar tissue.
But new research from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) suggests that this limitation may not be permanent. Instead, the capacity for regeneration may still exist — hidden within the body’s normal healing process.