A new review by researchers at Oregon Health & Science University’s Knight Cancer Institute and other universities highlights how advances in New Approach Methodologies and tissue engineering are offering powerful new tools to study the earliest stages of cancer development. New Approach Methodologies use human-relevant technologies such as in vitro tests, organoids, organs-on-a-chip and computational modeling to replace, reduce or refine animal testing.

Louisiana’s Environmental Influences on Child Health Outcomes, or ECHO program, has secured a share of $13 million in funding from the National Institutes of Health, or NIH. The award, which is for the program’s third award cycle, will support its efforts and research for five years. 

 

Founded in 2016, Louisiana’s ECHO program unites researchers from Pennington Biomedical Research Center, Ochsner Health System, Tulane University, and LSU Health Sciences Center New Orleans with leading pediatric clinicians at Our Lady of the Lake Children’s Hospital and Children’s Hospital in New Orleans. This collaboration brings together research capabilities and two free-standing children’s hospitals in the state, with a third under construction. 

The American Federation for Aging Research (AFAR), a national non-profit whose mission is to support and advance healthy aging through biomedical research, will host its annual Scientific Awards of Distinction ceremony in conjunction with the Annual Scientific Meeting of the Gerontological Society of America (GSA), on November 13, 2025 from 6:30pm-9:00pm ET in Room 306 of the Hynes Convention Center in Boston, Massachusetts. AFAR Scientific Director Steven N. Austad, PhD, will host the ceremony and present the awards to David B. Allison, PhD (2025 Irving S. Wright Award of Distinction), Lauren Hunt, PhD, RN, FNP (2025 Terrie Fox Wetle Rising Star Award in Health Services and Aging Research), and Arlan Richardson, PhD (2025 George M. Martin Lifetime Achievement in Mentoring Award). Award recipients will share lectures and remarks. A reception will follow. 

Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have uncovered a novel explanation for that resistance: Pancreatic tumors use a sugar-based disguise to hide from the immune system. The scientists also created an antibody therapy that blocks the sugar-mediated “don’t-attack” signal.

BUFFALO, NY — November 3, 2025 — A new research paper featured on the cover of Volume 17, Issue 10 of Aging-US was published on October 20, 2025, titled “Brain region-specific and systemic transcriptomic alterations in a human alpha-synuclein overexpressing rat model.”