Center for Vital Longevity Researchers from The University of Texas at Dallas have released the full dataset from the Dallas Lifespan Brain Study, a decade-long project designed to track brain and cognitive health as people age and distinguish neurologically healthy paths from those indicating a likelihood of decline. An article published on May 26 in Nature’s Scientific Data provides an overview of the project and outlines its significance.

A first-of-its-kind clinical trial clinical trial shows that therapeutic plasma exchange (TPE) combined with intravenous immunoglobin reduced biological age on average by 2.6 years, as measured by multi-omic biomarkers.  Results of the single-blind, placebo-controlled trial are published in the May 28, 2025, issue of Aging Cell, providing early data on the impact of TPE on biological age, supporting its potential for new disease and longevity applications. The research was led by scientists at Circulate Health, a company dedicated to harnessing the potential of TPE to advance human healthspan and lifespan, and the Buck Institute for Research on Aging.