3-Nov-2025
Protein plays unexpected dual role in protecting brain from oxidative stress damage
Johns Hopkins MedicinePeer-Reviewed Publication
New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the yellow pigment bilirubin.
- Journal
- Proceedings of the National Academy of Sciences
- Funder
- American Heart Association, Paul Allen Foundation Initiative in Brain Health and Cognitive Impairment, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, Solve-ME foundation, U.S. Department of Defense, the Valour Foundation, the Wick Foundation, Department of Veterans Affairs Merit Award, Louis Stokes VA Medical Center resources and facilities, Lincoln Neurotherapeutics Research Fund, Leonard Krieger Fund of the Cleveland Foundation, Meisel & Pesses Family Foundation