Urolithiasis is rising in prevalence, imposing a significant healthcare burden globally. Researchers from China analyzed global health database to reveal increase in total incidence and mortality from urolithiasis over the last 30 years. Age-standardized incidence and mortality rates were higher in males, particularly in countries with low socio-economic development. Notably, China has succeeded in reducing incidence rates of urolithiasis, and insights from their strategies will strengthen measures to reduce the disease burden in vulnerable regions.

A team of scientists at the Garvan Institute of Medical Research has discovered that inactivation of a stress pathway makes ER+ breast cancer cells ignore stress signals, allowing them to evade treatment.

Hundreds of thousands of people undergo corrective eye surgeries each year, including the laser-assisted technique known as LASIK. But the procedure involves cutting away tissue, which can result in negative side effects, prompting researchers to develop a less invasive technique that takes the laser out of LASIK by remodeling cornea tissue, rather than removing it, in initial animal tissue tests. The researchers will present their results at ACS Fall 2025.