How oocytes prepare for spindle assembly in prophase
Peer-Reviewed Publication
Updates every hour. Last Updated: 8-Oct-2025 12:11 ET (8-Oct-2025 16:11 GMT/UTC)
The microtubule organizing centers (MTOCs) of oocytes are essential for meiotic spindle assembly and for ensuring precise chromosome segregation. The detailed dynamic changes of MTOCs in germinal vesicle (GV) oocytes - a stage where early events of MTOC maturation happen - remain unclear. Recently, a study published in Science Bulletin explored the dynamics of MTOCs maturation in GV oocytes and disclosed the key factors involved in these processes. According to the investigation, MTOCs maturation is required for spindle assembly and may play an unrecognized role in oocyte aging.
The Korea Research Institute of Standards and Science (KRISS, President Lee Ho Seong) has developed a diagnostic platform that amplifies the unique optical signals of molecules by more than a hundred million times, enabling the precise detection and quantification of trace amounts of Alzheimer’s disease biomarkers in body fluids.
North American river otters eat, play and defecate in the same place. But their terrible food hygiene make them ideal for detecting future health threats in the environment, according to scientists. In a new study published Aug. 14, Smithsonian scientists analyzed the otters’ diets and “latrine” habitats in the Chesapeake Bay for the first time. They discovered river otters often eat food riddled with parasites—and that may not be a bad thing for the larger ecosystem.
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Solid-state batteries are widely recognized as the next-generation energy storage devices with high specific energy, high safety, and high environmental adaptability. However, the research and development of solid-state batteries are resource-intensive and time-consuming due to their complex chemical environment, rendering performance prediction arduous and delaying large-scale industrialization. Artificial intelligence serves as an accelerator for solid-state battery development by enabling efficient material screening and performance prediction. This review will systematically examine how the latest progress in using machine learning (ML) algorithms can be used to mine extensive material databases and accelerate the discovery of high-performance cathode, anode, and electrolyte materials suitable for solid-state batteries. Furthermore, the use of ML technology to accurately estimate and predict key performance indicators in the solid-state battery management system will be discussed, among which are state of charge, state of health, remaining useful life, and battery capacity. Finally, we will summarize the main challenges encountered in the current research, such as data quality issues and poor code portability, and propose possible solutions and development paths. These will provide clear guidance for future research and technological reiteration.
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