Muscle quality may hold clues to early cognitive decline
Peer-Reviewed Publication
Updates every hour. Last Updated: 4-Aug-2025 17:11 ET (4-Aug-2025 21:11 GMT/UTC)
Sarcopenia has been linked to dementia risk, but previous studies have focused on older adults. Japanese researchers assessed several muscle-related indices and cognitive function in middle-aged individuals. They found that phase angle—a measure of muscle quality—was strongly associated with cognitive function, especially in women. A significant association with memory performance was also observed in both genders. It could serve as an early marker for the risk of cognitive decline in clinical screenings.
City of Hope will present novel cancer treatment approaches and combinations, leading-edge targeted therapies, and supportive care interventions at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting taking place May 30 to June 3 in Chicago and online.
A collaborative team of researchers led by vision scientists from the School of Veterinary Medicine at the University of Pennsylvania have developed new tools to improve gene therapy in advanced stages of inherited retinal diseases (IRDs) such as retinitis pigmentosa and Leber congenital amaurosis. “This study addresses one of the biggest hurdles in IRD treatment: how to deliver effective gene therapy after a large portion of the retina has already degenerated,” says Raghavi Sudharsan of Penn Vet.