Certain glycans—sugar-like compounds with carbohydrate chains—containing galactose, may exhibit potential prebiotic properties that support human health. Identifying enzymes capable of breaking down these glycans is essential for unlocking their full potential. In a new study, researchers discovered a novel enzyme in the human gut that specifically targets a previously unexplored glycan called β-1,2-galactooligosaccharide, known for their prebiotic benefits. This discovery can open new avenues in prebiotic research, potentially enhancing human health.

Cancer and cardiovascular diseases (CVDs) share common risk factors, and treatments for cancer have the potential to increase the risk of CVDs. Researchers have elaborated on the importance of recognizing the indicators, patterns, predictive outcomes, and challenges associated with CVD risks in cancer patients and survivors. Proactive management and early detection are essential to improving the overall health outcomes and quality of life for patients with cancer.

A new Northwestern Medicine study publishing in Nature Medicine suggests a promising alternative to previous attempts to remove the sticky, toxic amyloid beta plaquest from brains with Alzheimer's Disease: enhancing the brain’s own immune cells to clear these plaques more effectively.

The findings could reshape the future of Alzheimer’s treatments, shifting the focus from simply removing plaques to harnessing the brain’s natural defenses.

The study is the first to use a cutting-edge technique called spatial transcriptomics on human clinical-trial brains with Alzheimer’s disease. The technique allows scientists to pinpoint the specific spatial location of gene activity inside a tissue sample. 

By analyzing donated brain tissue from deceased people with Alzheimer’s disease who received amyloid-beta immunization and comparing it to those who did not, the scientists found that when these treatments work, the brain’s immune cells (called microglia) don’t just clear plaques — they also help restore a healthier brain environment. 

New research by Flinders University has uncovered a potential marker that could provide valuable insights into the overall health of older adults living in long-term aged care facilities.

Led by Ph.D. candidate Sophie Miller in the College of Medicine and Public Health, the study found that a simple swab from the back of the throat, known as the oropharynx, may offer clues about health challenges faced by aged care residents.