The KU team parsed data from 276 youth from juvenile detention centers in the Midwest aged 11-17, who voluntarily answered questionnaires and provided demographic data to the researchers, which then was matched to categories of criminal charge. More than 35% of participants reported clinically significant symptoms of depression, and more than 26% reported elevated symptoms of anxiety.

A national survey of minimally invasive gynecology fellows shows ongoing off-label practices, frequent bag punctures, and cost-driven decisions that may put patients at risk.

The prevalence of Alzheimer disease (AD) is approximately two times higher in African Americans (AA) compared to White/European-ancestry (EA) individuals living in the U.S. Some of this is due to social determinants of health such as disparities in health care access and quality of education, biases in testing and higher rates of AD risk factors such as cardiovascular disease and diabetes in those who identify as African American.

Although many studies have examined differences in gene expression (measure of the amount of protein encoded by a gene) in brain tissue from AD cases and controls in EA or mixed ancestry cohorts, the number of AA individuals in these studies was unspecified or too small to identify significant findings within this group alone.

In the largest AD study conducted in brain tissue from AA donors, researchers from Boston University Chobanian & Avedisian School of Medicine have identified many genes, a large portion of which had not previously been implicated in AD by other genetic studies, to be significantly more or less active in tissue from AD cases compared to controls. The most notable finding was a 1.5 fold higher level of expression of the ADAMTS2 gene in brain tissue from those with autopsy-confirmed AD.