An Osaka Metropolitan University-led research team has developed a protein aggregation inhibitor that shows improved treatment results for mice with acute strokes. 

Scientists at ChristianaCare’s Helen F. Graham Cancer Center & Research Institute and the University of Delaware have discovered a surprisingly simple explanation for how our bodies stay so well-organized, even as billions of cells are replaced daily. In a new study, they identified just five basic rules—like when and how cells divide and die—that seem to guide how tissues like the colon maintain their structure over time. Using computer simulations, the team showed how these rules work together like choreography to keep tissues healthy and functioning. This breakthrough, which researchers call a potential “tissue code,” could help explain how our bodies heal, how diseases like cancer form, and even support global efforts like the Human Cell Atlas. It’s a powerful example of how math and medicine can come together to reveal the hidden instructions that keep us alive and well.

New survey data from the Orlando Health Spine Center reveals a significant difference among Americans on how to manage neck and back pain. 

Morphine is a potent opioid medicine utilized for the management of moderate to severe pain, particularly in palliative care, post-surgical recovery, and cancer treatment. But, it carries risks of addiction liability and respiratory depression. Thus, aim of the review was designed to insights into morphine: extraction, structural characterization, and pharmacological properties. A literature survey on scientific journals, books as well as electronic sources was performed for the content. This review delves into the multifaceted aspects of morphine, one of the most well-known opiate analgesics, focusing on its extraction, structural characterization, and pharmacological properties. The pharmacological profile of morphine is critically examined, highlighting its mechanisms of action, including its interactions with opioid receptors, and the resulting physiological effects. Also, the therapeutic applications of morphine is discussed in pain management, its potential for addiction, and the emergence of tolerance. By synthesizing current knowledge, this review provides a comprehensive understanding of morphine’s significance in medicine and its implications for future pharmacological developments.

Dear Editor,

Nipah virus (NiV) poses a significant threat to global health security due to its high fatality rate and the possibility of human-to-human transmission.1 This zoonotic virus can cause serious effect in both animals and humans.2 Although there are currently no approved vaccines or therapeutics for NiV, there have been promising advances in vaccine development in recent years, bringing us one step closer to curbing the impact of this deadly disease. NiV outbreaks have been reported in several countries in southern Asian countries in support of their statement, outbreaks are taken place annually in Bangladesh.3 The main route of transmission to human is through contact with infected animals, particularly, flying fox (Pteropus) natural reservoir of the virus. However, raising concerns about the pandemic potential of the virus and their impact on human-to-human transmission has also been documented.4