About The Study: The results of this study suggest that structural racism embedded in neighborhood conditions contributes to lung cancer development and provides evidence for policymakers and public health leaders working to reduce disparities. 

Relapsed/refractory peripheral and cutaneous T-cell lymphomas (R/R PTCL and CTCL) are aggressive blood cancers that often resist standard therapy. Patients with these lymphomas may require stem cell transplants, but the disease needs to be brought under control before patients can undergo this treatment. A new study by investigators from PETAL Consortium at Mass General Brigham found the combination of duvelisib and romidepsin to be effective, tolerable and safe for patients with R/R PTCL and CTCL. Their findings suggest that this drug combination offers a novel strategy to help these patients control the disease in order to be eligible for stem cell transplants. The results are published in Blood Advances.

Racism and sexism are “alarmingly normalised” within the structures and person-to-person interactions across the NHS, and the NHS has delayed acknowledging and learning from the evidence, says a report from the BMJ Commission on the Future of the NHS, published in The BMJ today.

A new study published in mBio details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the “macrodomain,” found in all coronaviruses such as SARS-CoV-2 and MERS-CoV. The findings point toward potential antiviral therapies to combat future coronavirus pandemics and confirm the importance of Mac1 to the viability of the virus.

Jingyan Han, PhD, assistant professor medicine at Boston University Chobanian & Avedisian School of Medicine, has received a three-year, $300,000 American Heart Association (AHA) Transformational Project Award. The award will enable her to use 3D printing to create and study artificial blood vessels to improve the understanding of vascular biology. This project will be done in collaboration with Yonghui Ding, PhD, an assistant professor of biomedical engineering at Worcester Polytechnic Institute.