Physical function is a crucial predictor of survival after heart failure
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Jun-2026 17:15 ET (22-Jun-2026 21:15 GMT/UTC)
A Japanese study of more than 7,400 patients has identified a genetic mismatch that sharply increases the risk of severe acute graft-versus-host disease (GVHD) following umbilical cord blood transplantation. The specific donor–recipient human leukocyte antigen mismatch triples the likelihood of life-threatening immune complications, and severe acute GVHD itself is associated with significantly worse survival. These findings may help refine donor selection and improve the safety and long-term outcomes of stem cell transplantation.
Primary percutaneous coronary intervention (PCI) is a life-saving procedure that is used to restore blood flow following an acute myocardial infarction.
An analysis of data from 21 European countries did not reveal a significant association between increased numbers of primary PCI procedures and reduced mortality rates.
Subsequent analyses will assess additional factors including the timing of the procedure relative to symptom onset, operator experience and variations in practice between different centres and countries.
Data such as these inform efforts to improve the treatment of cardiovascular disease across Europe and highlight the need for more effective prevention strategies.
Researchers at the University of Seville have analysed alterations in the cerebral cortex in people suffering from psychosis. Their findings show that psychosis does not follow a single trajectory, but rather its evolution depends on a complex interaction between brain development, symptoms, cognition and treatment. The authors therefore emphasise the need to adopt more personalised approaches that take individual differences into account in order to better understand the disease and optimise long-term therapeutic strategies.
Analysis of approximately 1604 studies from over three decades proves that delirium is a clinically highly relevant but scientifically often neglected complication in cardiology. Prevention can reduce the incidence of delirium by up to 40 percent. The review, led by the University Hospital Bonn (UKB), has now been published in the renowned European Heart Journal and provides systematic prevention strategies and innovative treatment recommendations.
Spontaneous coronary artery dissection (SCAD) is a common yet under-recognised cause of heart attacks in younger women, which is distinct from heart attacks caused by atherosclerosis.
Results from a prospective Serbian registry suggest that stent implantation is not beneficial in many patients with SCAD.
Further studies are needed to understand more about the condition and appropriate management strategies. The ESC’s large, multinational SCAD registry is underway.
Getting enough sleep may be more important for heart health than many busy professionals realize. A new multicenter study conducted by researchers from Kumamoto University and the National Cerebral and Cardiovascular Center, has found that insufficient sleep is linked to a higher risk of atrial fibrillation (AF) among working-age adults.