VIB researchers and colleagues have discovered a mechanism through which melanoma cells adapt and switch between two major proliferative and invasive states, revealing promising new targets for cancer therapy. The study, published in Nature Metabolism, reveals that alterations in iron metabolism and organelle crosstalk are central to melanoma cell plasticity—a key factor in tumor progression and resistance to treatment.

Patients in specialised psychiatric care face a variety of social risks that are intertwined, a new study from the University of Eastern Finland shows. Social risks tend to accumulate among the most vulnerable segments of the population. They include for example financial difficulties, housing challenges and violence.

Researchers demonstrated how a multifaceted intervention approach significantly improved the rate of dental varnish applications to help strengthen tooth enamel and prevent decay. The results exceeded the goal for the study, and improvements were consistent across insurance plans, race and ethnicity, providing an important framework for keeping teeth healthy.