Integrated metabolic analysis reveals cancer's energy secrets
Peer-Reviewed Publication
Updates every hour. Last Updated: 28-Dec-2025 02:11 ET (28-Dec-2025 07:11 GMT/UTC)
Researchers at The University of Osaka and Kanazawa University have developed a novel method for analyzing cancer metabolism, revealing new insights into cancer's inefficient energy process. This breakthrough, published in Metabolic Engineering, combines biological experiments with advanced information science techniques to uncover the role of cancer-specific inefficient metabolism.
Novel research shows that in approximately one third of countries and territories worldwide, population aging was the largest contributor to the growing burden of musculoskeletal disorders from 1990 to 2021. The new study in the Annals of the Rheumatic Diseases, published by Elsevier, is poised to inform targeted public health strategies and healthcare resource allocation to alleviate the global burden and economic impact of these disorders.
In August 2017, the National Natural Science Foundation of China (NSFC) launched the Major Research Plan “Dynamic Modifications and Chemical Interventions of Biomacromolecules” (implementation period 2017–2025). Through interdisciplinary research that integrates chemistry, life sciences, medicine, mathematics, materials science, and information science, its aim is to develop specific labeling methods and detection techniques for dynamic chemical modifications of biomacromolecules, elucidate the recognition mechanisms and biological functions of dynamic modifications in the regulation of cellular traits, and discover potential drug targets and corresponding lead compounds related to dynamic biomacromolecular modifications. Since its establishment, this Major Research Plan has achieved significant progress and original results in many aspects such as the dynamic properties of biomacromolecular chemical modifications, regulatory mechanisms, and chemical interventions. Recently, members of the expert group, management group, and secretariat of the program collaborated to systematically review representative research achievements obtained since the program’s implementation, and jointly published a review article in CCS Chemistry. This review provides important references for promoting development in related frontier fields, as well as for the future trend of integration between chemistry, life sciences, and medicine.
The Cardiovascular Research Foundation® (CRF®) and Jon DeHaan Foundation today announced the launch of the TCT AI Lab, a groundbreaking new program debuting at TCT® 2025, October 25–28 at the Moscone Center in San Francisco. The TCT AI Lab is a first-of-its-kind destination dedicated to integrating artificial intelligence into clinical practice. Over three intensive days, clinicians will progress from the fundamentals of AI to hands-on clinical applications – guided by leading innovators at the forefront of digital medicine.