A new Genomic Press interview explores Professor Siegfried Kasper's transformative contributions to modern psychiatry and treatment-resistant depression research. The Austrian psychiatrist, with over 800 publications and an H-index of 131, discusses his pioneering work demonstrating the biological basis of psychiatric disorders and revolutionizing treatments including SSRIs and intranasal esketamine. His research has fundamentally changed how the international medical community approaches depression, schizophrenia, and anxiety disorders.

Diesel engines have long been a cornerstone of transportation and industry, but their emissions have posed significant environmental and health challenges. A new study titled "Advancements in Diesel Emission Reduction Strategies: A Focus on Water-in-Diesel Emulsion Technology" explores innovative solutions to reduce harmful emissions while enhancing engine performance. This research delves into the potential of water-in-diesel emulsion (WiDE) technology, offering a promising pathway to a cleaner, more efficient future.

A research team from the Department of Microbiology under the School of Clinical Medicine in the LKS Faculty of Medicine of the University of Hong Kong (HKUMed), has successfully developed the world’s first ‘nasal organoid-based SARS-CoV-2 Neutralising Antibody Evaluation Platform’. The platform uses respiratory organoids that adequately model viral infection in the human respiratory tract, enabling accurate assessment of the effectiveness of antibodies and vaccines against SARS-CoV-2, the virus responsible for COVID-19.

A research team from the Department of Obstetrics and Gynaecology at the University of Hong Kong’s LKS Faculty of Medicine (HKUMed) has developed the world’s first artificial intelligence (AI) model that can accurately identify human sperm with fertilisation potential. This breakthrough could reshape diagnosis and assisted reproductive treatments worldwide.

A research team led by the Department of Medicine and the Department of Orthopaedics and Traumatology, under the School of Clinical Medicine, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), has uncovered a serious risk of joint infection following knee surgery, linked to allergy mislabelling. The study showed that patients incorrectly labelled as allergic to penicillin or other beta-lactam (BL) antibiotics face a significantly higher chance of developing periprosthetic joint infection (PJI) — a painful and costly infection that can arise following joint replacement surgery, which can also lead to major complications. This revelation has prompted the launch of Hong Kong’s first research-focused pharmacist-led pilot service for penicillin allergy assessment at HKUMed, aimed at addressing this critical healthcare issue. The research, underscoring the importance of accurate allergy documentation, was published in The Bone & Joint Journal.

Researchers from The University of Osaka have found that they can keep mouse uterine tissue alive outside of the body, allowing them to directly observe embryonic implantation and development. Their technique brings hope for patients with infertility, and may allow for the development of therapies to treat recurrent implantation failure and improve the chance of implantation success using assisted reproductive technologies.Researchers from The University of Osaka have found that they can keep mouse uterine tissue alive outside of the body, allowing them to directly observe embryonic implantation and development. Their technique brings hope for patients with infertility, and may allow for the development of therapies to treat recurrent implantation failure and improve the chance of implantation success using assisted reproductive technologies.