A new method developed by researchers at the Nuffield Department of Medicine, University of Oxford, could soon unlock the vast repository of biological information held in the proteins of ancient soft tissues. The findings, which could open up a new era for palaeobiological discovery, have been published today (28 May) in PLOS ONE.

Runaway cell death and inflammation triggered by severe trauma may be interrupted by a drug used to prevent alcohol abuse – and it may be particularly effective in females, according to new research led by University of Pittsburgh School of Medicine surgeon-scientists and published today in Science Translational Medicine.

In order to truly decolonize the field of global health, it may be necessary for institutions from the Global North to practice “ruinous solidarity,” according to a study published May 21, 2025 in the open-access journal PLOS Global Public Health by Daniel Krugman from Brown University, United States, and Alice Bayingana from the University of Sydney, Australia.   

Researchers at the Icahn School of Medicine at Mount Sinai have developed a machine learning tool that can help doctors manage blood sugar levels in patients recovering from heart surgery, a critical but often difficult task in the intensive care unit (ICU). The findings were reported in the May 27 online issue of NPJ Digital Medicine. After cardiac surgery, patients are at risk for both high and low blood sugar, which can lead to serious complications. Managing these fluctuations requires careful insulin dosing, but existing protocols often fall short due to the unpredictable nature of ICU care and differences among patients, say the investigators.

Physicians at MUSC Shawn Jenkins Children’s Hospital have developed a treatment algorithm to standardize care for children with sickle cell disease who present to the Emergency Department with a fever. With the new algorithm, emergency physicians confer with the hematology/oncology team to determine patients’ levels of risk, recommending that low-risk patients be treated as outpatients. The tool could at once improve the efficiency of care and decrease costs for patients and their families.