Smarter flow simulation model for analyzing blood flow in brain aneurysms
Peer-Reviewed Publication
Updates every hour. Last Updated: 31-Dec-2025 04:11 ET (31-Dec-2025 09:11 GMT/UTC)
To simulate blood flow inside brain aneurysms, researchers from Japan developed a computational method that combines 4D flow MRI, computational fluid dynamics, and data assimilation, which provides greater accuracy and efficiency. By focusing only on the aneurysm region, this approach significantly reduces computational cost while improving flow estimation. When validated on patient data, it outperforms conventional models—offering a practical tool for patient-specific risk assessment and treatment strategies.
Inflammation is a natural immune response, but when uncontrolled, it can worsen many diseases. Recent studies show that metabolism plays a surprising role in regulating this response. A new editorial in the Journal of Intensive Medicine highlights findings on the glyoxalase system, a metabolic pathway that helps immune cells tone down inflammation. This insight opens new possibilities for treating inflammatory diseases through metabolic targets, offering a promising direction beyond traditional immunosuppressants.
UCLA Health researchers have identified four distinct pathways that lead to Alzheimer's disease by analyzing electronic health records, offering new insights into how the condition develops over time rather than from isolated risk factors.
A new study conducted at Reichman University’s School of Sustainability presents an innovative tool to help decision-makers better understand the condition of streams and thereby advance their restoration and rehabilitation. The tool, called SESBI — the Stream Ecosystem Services and Biodiversity Index — is designed to measure what is called “stream health,” meaning the degree to which a stream functions ecologically and contributes to public welfare.
Researchers from the Josep Carreras Leukaemia Research Institute and the Aragon Health Research Institute have just presented a new strategy in the fight against T-cell Acute Lymphoblastic Leukaemia. This novel therapy is based on the use of CAR-T cells designed to target two specific markers of this type of leukaemia: the CD1a and CCR9 proteins. Preclinical results of this new therapeutic approach demonstrate both high efficacy and an excellent safety profile, paving the way for clinical development in the short term.