Vital intertwining
Università di TrentoPeer-Reviewed Publication
The researchers focused on the structure and dynamics of kinetoplast DNA, the mitochondrial genome of Trypanosomes, with an experimental study led by Edinburgh and a computational analysis that involved simulations conducted by UniTrento. Trypanosomes are a family of parasites (flagellated protozoa) that pose a risk to humans and animals because they are responsible for a number of tropical diseases, such as leishmaniasis and sleeping sickness, which are transmitted by the bite of flies, mosquitoes or other insects.
Quantifying the spatial organization and dynamics of the different regions of the mitochondrial genome of this blood parasite is a major challenge in biology. And this particular genome stands out for characteristics that can be useful for the development of new materials.
- Journal
- Nucleic Acids Research