New nanomedicine wipes out leukemia in animal study
Peer-Reviewed Publication
Updates every hour. Last Updated: 1-Nov-2025 02:11 ET (1-Nov-2025 06:11 GMT/UTC)
Scientists reengineered chemo drug into spherical nucleic acids (SNAs), a globular form of DNA. Team tested the repackaged therapy on an animal model of acute myeloid leukemia, a fast-moving blood cancer. SNAs easily entered cancer cells and killed them from the inside while sparing healthy cells.
University of Phoenix College of Doctoral Studies announced a new white paper, “Autonomy and Competitive Edge: Mentorship as a Solution,” by Louise Underdahl, Ph.D., doctoral instructor and a research fellow with the University’s Center for Educational and Instructional Technology Research (CEITR), exploring how structured mentoring programs can help organizations address a growing crisis of worker autonomy, reduce burnout and improve retention.
In a new study from Boston University Chobanian & Avedisian School of Medicine and BU’s College of Engineering, researchers used a special microscope called birefringence microscopy (BRM) paired with an automated deep learning algorithm to reliably count and map myelin damage across whole sections of the brain—something not feasible with other techniques. The ability to image and measure damage to myelin will lead to better understanding the patterns and extent that occurs with disease, injury and normal aging.
Focusing on the methodological challenges in adapting tissue optical clearing technology to large animals, this review systematically examines the key bottlenecks in transitioning from rodents to large animals, summarizes representative applications in neural circuit mapping and sensory organ visualization in large animal, and offers perspectives on future research directions.