Researchers have developed a fish-like robot that shows how some species of modern fish are able to walk on land, and could help unravel how early vertebrates evolved similar abilities hundreds of millions of years ago.

Researchers at IRB Barcelona develop a computational framework that creates molecules with selective activity in specific cell types, without the need to start from a predefined molecular target.

Published in Communications Chemistry, the new strategy combines predictive and generative AI to design new chemical entities with specific biological effects.

Experimental validation confirmed that several of the AI-generated molecules displayed the activity they were designed for, achieving a success rate superior to that of traditional screening methods.