Researchers propose a novel closed-loop system merging brain-computer interfaces and peripheral nerve stimulation to enable real-time, adaptive therapy for neuropsychiatric disorders like depression and ADHD. This approach dynamically tailors treatment to individual brain signals, overcoming limitations of one-size-fits-all methods. The technology promises precision neuromodulation, targeting specific neural circuits without invasive surgery.

Mehdi Bennis, Professor at the University of Oulu Finland and leading researcher at 6G Flagship, has been named one of the world’s Highly Cited Researchers for the sixth year in a row. The annual recognition by Clarivate identifies researchers whose work has consistently shaped the direction of scientific progress, placing them among the top 1% most cited by field and publication year.

A research team in South Korea has successfully developed a novel technology that combines nanoparticles with stem cells to significantly improve 3D bone tissue regeneration. This advancement marks a major step forward in the treatment of bone fractures and injuries, as well as in next-generation regenerative medicine.

Dr. Ki Young Kim and her team at the Korea Research Institute of Chemical Technology (KRICT), in collaboration with Professor Laura Ha at Sunmoon University, have engineered a nanoparticle-stem cell hybrid, termed a nanobiohybrid by integrating mesoporous silica nanoparticles (mSiO₂ NPs) with human adipose-derived mesenchymal stem cells (hADMSCs). The resulting hybrid cells demonstrated markedly enhanced osteogenic (bone-forming) capability.

Scientists at The University of Osaka developed a new 3D culture scaffold by integrating the strong cell-adhesive domain of laminin-511 into a clinically used fibrin gel, creating a chimeric protein called Chimera-511. This laminin-functionalized fibrin gel supports efficient 3D expansion of human iPS cells while maintaining pluripotency. As a chemically defined, xeno-free material, it offers a promising alternative to Matrigel and a potential platform for clinically applicable organoids and regenerative therapies.