2-Sep-2025
New research identifies a natural guardian of blood vessel health
MDI Biological LaboratoryPeer-Reviewed Publication
Summary/Description (1–2 sentences):
An international research team led by MDI Biological Laboratory has discovered that a little-known molecule, heparanase 2 (Hpa2), plays a critical role in maintaining blood vessel integrity. Published in Arteriosclerosis, Thrombosis, and Vascular Biology, the findings suggest Hpa2 may provide a natural mechanism to prevent and treat diseases linked to vascular leakiness, including diabetic retinopathy, macular degeneration, kidney disease, cardiovascular disease, and cancer.
An international research team led by MDI Biological Laboratory has discovered that a little-known molecule, heparanase 2 (Hpa2), plays a critical role in maintaining blood vessel integrity. Published in Arteriosclerosis, Thrombosis, and Vascular Biology, the findings suggest Hpa2 may provide a natural mechanism to prevent and treat diseases linked to vascular leakiness, including diabetic retinopathy, macular degeneration, kidney disease, cardiovascular disease, and cancer.
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Funder
- Scott MacKenzie Foundation, German Research Foundation (DFG), NIH/National Institute of General Medical Sciences, NIH/National Institute of General Medical Sciences