Liver organoids, three-dimensional structures derived from stem cells or hepatic progenitors, have emerged as a transformative technology. Unlike traditional two-dimensional cultures or animal models, organoids faithfully recapitulate the complex architecture and functionality of native liver tissue. This review summarizes recent advancements in liver organoid technology, detailing their development, classification, and key applications.

The studies ‘Unmasking Hidden Androgen Rhythms with a Real-Time AI-Enhanced Testosterone Patch’ and ‘Endocrine Rhythm Integrity: A Novel AI-Derived Metric of Menstrual Cycle Health of the Cycle Length’ will be available as a poster /e-poster from Saturday 9 May 2026 at the European Congress of Endocrinology at the Prague Congress Centre (PCC) in the Czech Republic.

Dissolved organic matter, a complex mixture of carbon-containing molecules found in soils, rivers, lakes, wetlands, and sediments, plays a central role in how carbon moves through the environment. It can feed microbes, bind pollutants, influence nutrient availability, and affect how much carbon is stored or released as carbon dioxide. Yet scientists are still working to understand why some dissolved organic matter is quickly consumed by microbes, while other portions persist much longer.

Researchers have developed a new biochar-based composite that can capture uranium from water while also converting part of it into a less toxic chemical form, offering a potential strategy for recovering uranium from seawater and supporting future nuclear energy resources.

Environmental scientists and water resource managers need precise, high-resolution maps to reveal areas that farmers should avoid when planting crops, to limit polluting waters with phosphorus from fertilizer or manure. Making those maps has depended on an expensive, sometimes unavailable technology, but a team led by Penn State researchers has developed a cheaper approach that can be just as effective.

The molecule cAMP, which plays essential roles in mammalian cells, is less well understood in plants. In a new Science Advances paper, researchers from the Institute of Science and Technology Austria (ISTA) and international collaborators demonstrate that plants use two forms of cAMP in parallel to regulate normal cellular processes and respond to stress, while maintaining crosstalk between them. That crosstalk provides redundancy, so that if one fails, the other can compensate, allowing plants to respond more robustly to a wider range of environmental factors. Ultimately, the findings could help improve crop resilience and productivity in a rapidly changing climate. 

The Department of Energy’s Oak Ridge National Laboratory has named Katherine (Kate) Evans as associate laboratory director for the Biological and Environmental Systems Science Directorate (BESSD). Evans will lead the directorate as it advances the science and technology needed to strengthen energy security, safeguard infrastructure and accelerate biotechnology innovation.