Biology
Updates every hour. Last Updated: 24-Oct-2025 18:11 ET (24-Oct-2025 22:11 GMT/UTC)
Scientists use heterocycles to target cancer toward safer, smarter treatments
FAR Publishing LimitedThe way a drug works and what it targets in the body are key factors in how effectively it can kill harmful cells. This work looks at a group of important proteins called receptor tyrosine kinases, which are often involved in diseases like cancer. Scientists have found that certain chemical structures—called heterocycles, such as pyrimidine, thiazole, imidazole, indole, acridone, and triazine—can be used to make drugs that target these proteins. With some changes, these compounds could also be designed to affect other disease pathways in the future.
"Shrinking" cod: how humans have altered the genetic make-up of fish
Helmholtz Centre for Ocean Research Kiel (GEOMAR)Peer-Reviewed Publication
25 June 2025/Kiel. Overfishing not only depletes fish stocks — it also alters the genetic blueprint of marine life. In the central Baltic Sea, cod (Gadus morhua) have not only become scarcer, but also significantly smaller than in the past. Researchers at the GEOMAR Helmholtz Centre for Ocean Research Kiel have now shown for the first time that Eastern Baltic cod grow markedly more slowly than they once did, and that this change is reflected in their genome. Intensive fishing pressure triggers genetic responses in overexploited stocks, with long-term implications for their future development. The findings are published today in the journal Science Advances.
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- Science Advances
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- DFG Research Training Group TransEvo
Scientists advance prospects for permanently putting aids virus into dormant state using gene therapy
Johns Hopkins MedicinePeer-Reviewed Publication
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- Science Advances
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- NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health
Duffy, Wagoner awarded NCInnovation grants
University of North Carolina at GreensboroGrant and Award Announcement
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- NCInnovation
New study shows how biomass changed over 500 million years
Stanford UniversityPeer-Reviewed Publication
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- Current Biology
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- U.S. National Science Foundation
Orangutans nap to make up for lost sleep
Max Planck Institute of Animal BehaviorPeer-Reviewed Publication
Power naps: wild orangutans nap to catch up on lost sleep
Sleep in the wild: scientists studied wild adult orangutans to uncover what affects their sleep and how they compensate for lost sleep
Evolution of sleep: study offers new insights into the evolution of behavioral strategies to ensure that animals get the sleep they need
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- Current Biology