Spatial profiling of muscle-invasive bladder cancer reveals how different tumor cell states are organized within individual tumors

Bladder tumors are not simply “luminal” (more differentiated) or “basal” (less differentiated) but often contain both cell states arranged in distinct spatial patterns

Luminal tumor cores and basal-like invasive regions respond differently to treatments

Findings provide a framework that may inform precision therapy strategies tailored to the spatial tumor cell landscape of bladder cancer

A new study sheds light on how the ancestors of modern land plants survived one of the most challenging aspects of life outside water: exposure to harmful ultraviolet (UV) radiation. By examining a microscopic alga closely related to the earliest land plants, researchers have uncovered a sophisticated and dynamic system for coping with sunburn – one that likely helped plants to colonize land over 500 million years ago. The results were published in Current Biology.

Scientists analyzed more than 350 over-the-counter probiotics sold at the three largest pharmacy chains in the United States. Here's what they found.

Orangutans seek out plants with antimicrobial, anti-inflammatory and wound-healing properties, new research shows.

By teaching an AI to use optical tweezers, researchers from the University of Gothenburg and Chalmers University of Technology, have sped up the analysis of life’s smallest components. The AI platform captures particles, takes measurements and loads new samples, all without human intervention.

A global study of more than 5,100 species of plants and animals challenges long-held assumptions about which species are most threatened by climate change. Almost half the species included in the study went locally extinct at the warmest part of the region where they were previously found.