One of the biggest challenges in cancer treatment is that certain cancers reappear after chemotherapy—and an aggressive type of blood cancer called acute myeloid leukemia (AML) is notorious for this. Now, new research from The Jackson Laboratory (JAX) points to a previously unknown molecular mechanism behind that chemoresistance, and a way to potentially disarm it.

Kyoto, Japan -- As space programs evolve and we continue to mistreat our own planet, human dreams of space tourism and planetary colonization seem increasingly common. However, features of spaceflight such as gravitational changes and circadian rhythm disruption -- not to mention radiation -- take a toll on the body, including muscle wasting and decreased bone density. These may even affect our ability to produce healthy offspring.

Studying the impact of spaceflight on germ cells -- egg and sperm precursor cells -- is particularly important because they directly influence the next generation, and any irreversible damage done to these will likely be transmitted to offspring. Previous examinations of embryonic stem cells that have undergone spaceflight have revealed abnormalities, but the exact cause of the damage has remained unknown.

This inspired a team of researchers at Kyoto University to test the potential damage to spermatogonial stem cells during spaceflight and the resulting offspring. The team utilized stem cells from mice, which have a much shorter reproductive life span than humans.

Media Invitation – IJCAI 2025, Montréal, Canada
Artificial Intelligence for a Better World – Since 1969

The 34th International Joint Conference on Artificial Intelligence (IJCAI) takes place August 16–22, 2025 in Montréal, Canada, bringing together over 2,000 AI researchers, practitioners, and thought leaders. Guided by the theme “AI at the service of society”, IJCAI 2025 features world-class keynote speakers, award-winning researchers, thematic tracks on AI for Social Good, Human-Centred AI, and AI, Arts & Creativity, as well as admission free public events like the AI Lounge: Between Wonder and Caution.

Highlights include talks by Yoshua Bengio, Heng Ji, Luc De Raedt, Bernhard Schölkopf, and IJCAI 2025 awardees Aditya Grover, Rina Dechter, and Cynthia Rudin. The program also showcases AI-driven competitions, an AI Art Gallery, and discussions on ethics, creativity, and global impact.

Full program & details: https://2025.ijcai.org
Media contact: mrozman@ijcai.org

Neurons in the gut produce a molecule that plays a pivotal role in shaping the gut’s immune response during and after inflammation, according to a new study by Weill Cornell Medicine investigators. The findings suggest that targeting these neurons and the molecules they produce could open the door to new treatments for inflammatory bowel disease and other disorders driven by gut inflammation.

The Okinawa Institute of Science and Technology (OIST) Associate Professor Paola Laurino has been selected as one of the top 10 global awardees in the Life Sciences category of the Falling Walls Science Breakthrough, presented by Germany’s Falling Walls Foundation.  

Extracellular vesicles (EVs) are tiny particles released by cells that help control egg development. In a recent review, researchers from China explored how EVs influence oocyte health by transferring important molecules between cells. The article discusses how EV function changes under disease conditions and how this affects fertility. It also highlights the growing potential of therapeutic EVs to improve egg quality and treat ovarian disorders, offering new possibilities for advancing reproductive medicine.