Maternal infection disrupts newborn brain development: A link to neurodevelopmental disorders
Peer-Reviewed Publication
Updates every hour. Last Updated: 2-May-2025 22:09 ET (3-May-2025 02:09 GMT/UTC)
A new study in Brain Medicine explores how maternal immune activation (MIA) affects hippocampal neuron function in newborn rat offspring. The research demonstrates that MIA significantly alters neuronal excitability, reducing glutamatergic neurotransmission—a crucial factor in neurodevelopmental disorders. These findings provide critical insights into how prenatal infections may increase the risk of autism, schizophrenia, and depression.
While some captive birds have been reported to be able to imitate human-made sounds, such as human words and coughs, ornithologists from China first quantitatively described human-made sounds, the sounds of electric mopeds, imitated by Chinese Blackbirds living in the wild.
Up to 25% of new mothers suffer from postpartum depression, which can significantly impact their parenting behavior and the wellbeing of their children. A new study from the University of Illinois Urbana-Champaign looks at long-term effects of early maternal depression on children, underscoring the need to provide adequate support for mothers who might be struggling.
By unraveling the complex choreography of cellular machinery, Michigan State University researchers are helping identify the next generation of drug targets and cancer therapies.
Led by Jian Hu and Kennie Merz, the MSU team has unveiled new insights into a family of proteins that, while vital for cellular functions, are also linked to an array of diseases such as breast, ovarian and pancreatic cancers.
Understanding these dynamic proteins found in cell membranes — called Zrt-/Irt-like proteins, or ZIPs for short — will contribute to the search for cutting-edge drug therapies and the improved health of patients.