How did plants evolve the ability to transport massive amounts of protein into seed vacuoles?
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Updates every hour. Last Updated: 24-Jun-2025 02:10 ET (24-Jun-2025 06:10 GMT/UTC)
In a recent study published in Current Biology, a research team led by Professor Takashi Ueda of the National Institute for Basic Biology and Associate Professor Masaru Fujimoto of the University of Tokyo has revealed the molecular steps that led to the emergence of this plant-specific vacuolar transport system. Their work shows that the acquisition of this pathway was driven by the stepwise neofunctionalization of a membrane fusion protein called VAMP7.
An unprecedented international effort to decode how cells manage the transport of chemical substances has culminated in four groundbreaking studies published in Molecular Systems Biology. Led by Giulio Superti-Furga at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, and supported by an international consortium of academic and pharmaceutical partners under the European Union's Innovative Medicines Initiative, this decade-long project provides the first comprehensive functional blueprint of chemical transport pathways in human cells.
The Universitat Autònoma de Barcelona (UAB) forms part of an international consortium that is preparing the Tree of Sex project, an ambitious initiative aimed at decoding the evolutionary complexity of reproductive strategies across eukaryotic Life.
While Alzheimer’s disease is mostly considered a disorder of the brain, emerging evidence suggests that the condition also affects other organs of the body. Working with the laboratory fruit fly, researchers at Baylor College of Medicine, the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital (Duncan NRI) and collaborating institutions provide a new understanding of how Alzheimer’s disease affects different tissues across the entire body. The findings, published in Neuron, reveal new insights into brain-body communication in neurodegeneration and pave the way for identifying novel biomarkers and therapeutic targets for Alzheimer’s disease.