Article Highlights
Updates every hour. Last Updated: 1-Dec-2025 16:11 ET (1-Dec-2025 21:11 GMT/UTC)
Discovery paves the way to prevent multidrug resistance in cancer cells
Okayama University of Science- Journal
- Scientific Reports
Machine learning takes biochar dye cleanup to the next level
Biochar Editorial Office, Shenyang Agricultural University- Journal
- Carbon Research
Bacteria reveal hidden powers of electricity transfer
King Abdullah University of Science & Technology (KAUST)- Journal
- The ISME Journal
KU researcher's new work focuses on ‘Indigenous fire sovereignty’
University of KansasScholar finds evidence from far-flung global regions about benefits of Indigenous fire sovereignty. Melinda Adams applying her knowledge to the land in cooperation with tribe in Kansas.
- Journal
- Proceedings of the National Academy of Sciences
New five-axis machining method boosts industrial productivity and paves way for smarter manufacturing
Tsinghua University PressFive-axis machining plays a pivotal role in manufacturing complex industrial components. In a recent study, researchers introduced a surface-partitioning and iso-scallop field-based strategy tailored for non-spherical cutting tools. By adaptively dividing machining surfaces and generating smooth tool orientations, the method significantly shortens tool paths, reduces machining time, and improves surface quality. This breakthrough not only enhances industrial productivity but also provides a foundation for integrating intelligent optimization in smart manufacturing.
- Journal
- Chinese Journal of Aeronautics
A balancing act: How SmCSN5 fine-tunes medicinal compound biosynthesis in red sage
Nanjing Agricultural University The Academy of ScienceThe study reveals a new regulatory mechanism controlling the biosynthesis of tanshinones and phenolic acids in Salvia miltiorrhiza (Danshen), a key herb in traditional Chinese medicine. Researchers identified SmCSN5, a subunit of the COP9 signalosome complex, as a stabilizing partner of the transcription factor SmMYB36, which simultaneously promotes tanshinone synthesis and represses phenolic acid formation. SmCSN5 prevents SmMYB36 degradation through the ubiquitin–proteasome pathway and enhances its transcriptional activity under methyl jasmonate induction. This work uncovers a post-translational control layer coordinating secondary metabolism in medicinal plants, providing new insights for metabolic engineering to selectively enhance pharmacologically active diterpenoid compounds.
- Journal
- Horticulture Research
Genetic study reveals why some tea plants are more vulnerable to insects
Nanjing Agricultural University The Academy of ScienceSalicylic acid (SA) plays a pivotal role in plant defense, yet its genetic regulation in tea remains largely unexplored. By analyzing 299 tea accessions through genome-wide association studies (GWAS) and genotyping-by-sequencing (GBS), researchers uncovered a key gene—CsNCED1—that negatively regulates SA-mediated immune responses. Overexpression of this gene increased abscisic acid (ABA) levels and weakened pest resistance by suppressing SA biosynthesis and its receptor signaling pathway. The findings reveal the antagonistic interplay between ABA and SA in determining tea plants’ susceptibility to biotic stress, offering crucial genetic resources for marker-assisted breeding of insect-resistant cultivars.
- Journal
- Horticulture Research
How grape berries adapt their carbon metabolism to cope with limited sugar supply
Nanjing Agricultural University The Academy of Science- Journal
- Horticulture Research
Historical high prices drive seasoned equity offerings in China
Shanghai Jiao Tong University Journal CenterAbstract
Purpose – We are the first to investigate the relationship between seasoned equity offerings (SEOs) and anchoring on historical high prices in China.
Design/methodology/approach – We use the ratio of the recent closing price to its historical high in the previous 12–60 months (anchoring-high-price ratio) to study its impact on the market timing of SEOs.
Findings – Empirical results show that the anchoring-high-price ratio significantly and positively affects the probability of additional stock issuances. Contrary to the USA market, the Chinese stock market reacts negatively to the SEOs at historical highs. Moreover, the anchoring-high-price ratio exacerbates the negative effect of announcements and leads to long-term underperformance. Finally, we investigate the impact of the anchoring-high-price ratio on a company’s capital structure, showing that the additional issuance anchoring on historical highs reduces the company’s leverage ratio in the long run. Overall, our findings support the anchoring theory and can help understand better the anchoring behavior of managers and the company’s decision on additional stock issuances.
Originality/value – We are the first to use the anchoring-high-price ratio to study the timing of SEOs. We find that the anchoring-high-priceratio positively affects the probability of SEOs. Unlike the USA, the Chinese stock market reacts negatively to SEOs at high prices. SEOs anchoring on historical highs reduce a firm’s leverage ratio in the long run. Finally, our results support the anchoring theory.
- Journal
- China Finance Review International