The increase in precision agriculture has promoted the development of picking robot technology, and the visual recognition system at its core is crucial for improving the level of agricultural automation. This paper reviews the progress of visual recognition technology for picking robots, including image capture technology, target detection algorithms, spatial positioning strategies and scene understanding. This article begins with a description of the basic structure and function of the vision system of the picking robot and emphasizes the importance of achieving high-efficiency and high-accuracy recognition in the natural agricultural environment. Subsequently, various image processing techniques and vision algorithms, including color image analysis, three-dimensional depth perception, and automatic object recognition technology that integrates machine learning and deep learning algorithms, were analyzed. At the same time, the paper also highlights the challenges of existing technologies in dynamic lighting, occlusion problems, fruit maturity diversity, and real-time processing capabilities. This paper further discusses multisensor information fusion technology and discusses methods for combining visual recognition with a robot control system to improve the accuracy and working rate of picking. At the same time, this paper also introduces innovative research, such as the application of convolutional neural networks (CNNs) for accurate fruit detection and the development of event-based vision systems to improve the response speed of the system. At the end of this paper, the future development of visual recognition technology for picking robots is predicted, and new research trends are proposed, including the refinement of algorithms, hardware innovation, and the adaptability of technology to different agricultural conditions. The purpose of this paper is to provide a comprehensive analysis of visual recognition technology for researchers and practitioners in the field of agricultural robotics, including current achievements, existing challenges and future development prospects.

A research team led by Dr. Young-Min Kim and Dr. Byeong-Chan Suh from Lightweight Materials Research Division at the Korea Institute of Materials Science(KIMS) has developed the world's first solid-state hydrogen storage material capable of storing and transporting hydrogen safely without the need for high-pressure tanks or cryogenic systems.

In recent years, the field of clinical laboratory medicine has witnessed remarkable advancements, driven by technological innovations, interdisciplinary research, and the growing demand for precision diagnostics. As Co-Editor-in-Chief, I am pleased to introduce LabMed Discovery (LMD), a new open-access, peer-reviewed journal dedicated to facilitating scholarly communication and fostering innovation in laboratory medicine, in vitro diagnostics, and emerging diagnostic technologies.

LabMed Discovery is proudly sponsored by Ruijin Hospital and Shanghai Jiao Tong University and serves as the official journal of the College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine. With a clear mission to “lead the innovation of laboratory medicine technology and promote international exchanges in medical technology,” LMD aspires to be a leading platform for global researchers and clinicians to disseminate cutting-edge research, novel diagnostic methodologies, and transformative clinical applications.

MicroRNAs (miRNAs) are endogenous single-stranded non-coding RNAs approximately 22 ​nt in length, which play a regulatory role in various biological processes by targeting and inhibiting protein-coding gene transcripts. Among the wide range of miRNAs, miR-668 exhibits abnormal expression patterns in different diseases, including head and neck squamous cell carcinoma (HNSC), hepatocellular carcinoma (HCC), breast cancer (BrC), ischemic acute kidney injury (ischemic AKI), myocardial infarction (MI), ischemic stroke (IS), Parkinson’s disease (PD), smoking-related interstitial fibrosis (SRIF), premature aging, and non-segmental vitiligo (NSV), among others. The expression of miR-668 is regulated by various upstream factors, including other non-coding RNAs and endogenous proteins. Functionally, miR-668 targets 6 protein-coding genes (SDF-1, Dvl1, BTG2, MTFP1, FHIT, and NFKBIA) and is involved in 3 signaling pathways: the Drp signaling pathway, NF-κB signaling pathway, and NLRP3 signaling pathway. Notably, miR-668 has contrasting effects depending on the context; it can promote the development and metastasis of HCC and induce radiation resistance in BrC cells, while also promoting aging and inhibiting HNSC progression in human keratinocytes. Furthermore, miR-668 exhibits anti-apoptotic effects, alleviates ischemia/reperfusion injury, improves intracerebral expansion, relieves hydrocephalus, and has prognostic value in gastric cancer (GC), HCC, and BrC, with high expression predicting poor outcomes. Notably, the cancer drugs melatonin and Pterostilbene (Ptero) exert their therapeutic effects by modulating miR-668. Future studies should focus on validating the reliability of miR-668 as a biomarker and elucidating the specific mechanisms through which miR-668 participates in cancer therapy.

Objective: Paper cups are mostly used for consuming beverages. These cups have an interior laminated hydrophobic thin film coated with polyethene and copolymers. During association with hot water or beverages ions like nitrite, chloride, fluoride and microplastic particles were released into water. Deposition of these particles has serious health effects in human. So, the objectives of the present study are to evaluate the degradation of the microplastic particles as a result of exposure to hot water. Methods: Different characterization techniques like UV-Vis spectroscopy, scanning electron microscopy, Gas chromatography-mass spectroscopy, Fourier transform infrared spectroscopy and Inductively coupled plasma optical emission spectroscopy are used to identify microplastic particles. Information about microplastic content in such samples is limited, yet most of the analytical methods used are very time-consuming. Results: Sample preparation and detection require sophisticated analytical tools and eventually require high user knowledge. This research shown that microplastics can leach from the lining of disposable cups into the beverage within minutes of contact with hot liquids. GCMS report shows that Phthalates compound and chemical exposure affect the endocrine system which interferes with hormone function. When exposed to hot water, the plastic coatings start to break down and the compounds like Diethyl phthalate, Di-2-ethylhexyl-adipate, Butylated hydroxytoluene, Benzotriazole, Styrene, Vinyl chloride were found in the hot water. Some scientists have shown that certain bacterial enzymes can hydrolyze and degrade the microplastic compound. Conclusions: This research discusses paper cup microplastic compounds and the binding affinity of detoxification enzyme interaction have been discussed in silico. However, this research recommends to opting for reusable cups made of glass, steel, and safer materials like soil-made cup.

As part of the Healthy China Action, the prevention and treatment of hemophilia has attracted widespread attention in China. This article systematically summarizes the current status and progress of hemophilia in the country in terms of prevalence, diagnostic technology, prevention methods, and treatment plans.

This study reveals the step-wise establishment of nuclear speckle-associated domains (SPADs) during mouse embryogenesis. Using optimized CUT&Tag, researchers found paternal SPADs dominate pre-ZGA stages, coordinating sequential gene expression and 3D genome reorganization. SPADs form two classes (primary and ZGA-dependent secondary), regulated by factors like Nipbl and Gata6, linking chromatin dynamics to developmental programming.

This study reported that pasteurized Akkermansia muciniphila (pAKK) promotes the differentiation of intestinal microfold cells (M cells) and increases the expression of the GP2 receptor via the TLR2-MyD88-NF-κB pathway, thereby enhancing the ability of Salmonella Typhimurium (STm) to invade Peyer's patches and leading to aggravated infection in mice. However, pAKK had no significant effect on the extracellular pathogen Citrobacter rodentium (Cr). Experiments showed that pre-treatment with pAKK significantly increased the expression of M cell markers and the number of gut lymphoid tissues, with effects depending on TLR2 signal activation mediated by the Amuc_1100 protein, independent of the canonical RANKL pathway. This study cautions that the application of probiotics should take pathogen specificity into account, as pAKK may increase the risk of infection by pathogens that rely on M cell invasion.