People with type 1 diabetes (previously called juvenile diabetes) are 4.29 times more likely to develop bladder cancer, according to a systematic review and meta-analysis by researchers at the Keck School of Medicine of USC. The new analysis is the first to control for the effects of tobacco smoking, a factor that likely obscured the heightened risk in earlier studies. Because smoking is a strong contributor to bladder cancer, research designed to identify other risk factors must control for—or separate out—the influences of smoking from influences of other proposed causes. But no prior studies on type 1 diabetes and cancer had done so. The research team suspected that people with type 1 diabetes may smoke less than the general population. To investigate that idea the research team gathered data from authoritative sources such as the World Health Organization to estimate smoking prevalence in populations where the original studies were conducted. The patterns the team found using a technique called meta-regression supported the team’s hypothesis, helping explain why earlier analyses failed to detect a connection. After accounting for patterns of smoking, they estimated that people with type 1 diabetes were 4.29 times more likely to get bladder cancer.

 

 

 

A landmark multi-country clinical trial has shown that a structured, sustainable approach to infection prevention and treatment can save women’s lives, cutting severe maternal infections and deaths by about one-third (32%) compared to usual care. The maternal programme of prevention and treatment (APT-Sepsis) was developed by researchers at the University of Liverpool, the World Health Organization (WHO) and the UN’s Special Programme in Human Reproduction (HRP).

Researchers revealed important genetic components that affect bone density in children and adolescents.

Point-of-care ultrasound is a technique proven to help physicians diagnose medical problems faster and more accurately, but there is no national consensus on how to train physicians to use it. New research, led by CU Anschutz physicians and alumni, works 

Two researchers at Kennedy Krieger Institute received $5.5 million to start an innovative three-year neurorehabilitation program aimed at improving the brain health of pediatric cancer patients with brain tumors.

A new study published in Management Science shows that question-and-answer messaging can significantly increase curiosity, drive topic-specific information seeking and in some cases promote healthier behaviors. The research demonstrates that framing information as a question, rather than a direct statement, can meaningfully increase engagement across diverse populations and communication channels.

A new research letter published in JAMA Health Forum highlights major gaps in how opioid use is tracked among older adults receiving post-acute care under Medicare. Researchers found that Medicare Part D claims significantly underreport opioid dispensing for patients admitted to skilled nursing facilities after hospitalization — a shortcoming that may hinder effective pain management, patient safety monitoring, and health policy decisions.