Brain metastases often occur as a result of advanced cancer and, despite medical innovations, are still associated with a poor prognosis. Now, an international expert committee led by the Medical University of Vienna and the Ludwig Maximilian University Hospital (LMU) in Munich has taken an important step towards improving diagnostics and therapy monitoring. A special imaging procedure, amino acid PET, can not only improve patient care, but also advance research into the development of new treatment approaches. The first standardised criteria for the use of this method have now been published in the top journal Nature Medicine.

Researchers from Mass General Brigham and the Mass General Brigham Gene and Cell Therapy Institute – a hub of innovation dedicated to accelerating groundbreaking research, conducting clinical trials and developing FDA-approved treatments in gene and cell therapy – will present new data at the 2025 American Society of Gene and Cell Therapy (ASGCT) Annual Meeting, taking place May 13-17 in New Orleans.

Cryptic peptides, which are expressed in pancreatic cancer cells, could be promising targets for T-cell therapies that attack pancreatic tumors, according to a study from MIT and the Dana-Farber Cancer Institute.