Results from two studies find new implant restores blood pressure balance after spinal cord injury. In a rare double publication in both Nature and Nature Medicine, a pair of landmark studies by Dr. Aaron Phillips, PhD, UCalgary, Dr. Grégoire Courtine, PhD, EPFL, and Dr. Jocelyne Bloch, MD, UNIL, describe the development of a targeted therapy to address blood pressure regulation in 14 participants across four clinical studies conducted at three separate medical centers in Canada, Switzerland, and the Netherlands. The implantable neurostimulation system evaluated in these studies was developed by ONWARD Medical. The company recently received FDA approval to initiate a pivotal trial of this therapy, which is expected to involve approximately 20 leading neurorehabilitation and neurosurgical research centers across Canada, Europe and the United States.

 

Armida Labs, Inc., a University of California, Riverside startup company, has been awarded a $2.25 million Small Business Innovation Research grant from the National Cancer Institute of the National Institutes of Health. The grant will support preclinical investigational new drug (IND) application studies, which are critically required before human clinical trials can be initiated.

A survey study of families with puppies in the U.K. has identified multiple mental health challenges alongside benefits of ownership for adults and kids alike, suggesting that a mental health boost should not be the main motivator behind getting a puppy. Rowena Packer of the Royal Veterinary College, U.K., and colleagues present these findings in the open-access journal PLOS One on September 17, 2025.

Pathogens driving infections in both healthcare and community settings, including the growing threat of sexually transmitted infections, have been identified as posing significant antimicrobial resistance risks, according to a new Canadian evidence-based framework

Two healthcare workers get COVID-19 vaccinations on the same day. Both show strong antibody responses initially, but six months later one stays healthy while the other contracts the virus. A new study published in Science Translational Medicine could help explain this difference. Researchers tracked individuals’ antibody levels after vaccinations and identified four distinct patterns of immune response after the first booster vaccination. Notably, the group that started with the highest antibody levels but experienced a faster decline were infected earlier. People with lower blood levels of IgA(S) antibodies, which protect the nose and throat, were also at higher risk. The findings suggest that monitoring how antibody levels change over time could assist in identifying individuals at greater risk of infection.