The international system for assessing organ dysfunction in critically ill patients is updated after thirty years
Peer-Reviewed Publication
Updates every hour. Last Updated: 26-Dec-2025 20:11 ET (27-Dec-2025 01:11 GMT/UTC)
The iMetaMed framework illustrates the integrative vision for medicine by dissolving disciplinary boundaries. Four major modules are highlighted: (1) Molecular & Computational Frontiers, represented by AlphaFold3 protein structure prediction (precision diagnostics), GeneCompass federated learning, and single-cell transcriptome integration; (2) AI-Enabled Clinical Translation, including AI-driven drug discovery, virtual cell modeling, and generative virtual staining; (3) Data Science & Infrastructure, featuring big data methodologies, dual-axis slicing, semantic dictionaries, and accelerated Biobank data extraction; and (4) Health Systems & Public Impact, encompassing telemedicine applications, open science, transparent peer review, multilingual dissemination, and diversity-oriented equity frameworks. At the core, iMetaMed envisions a seamless continuum from molecules to clinical practice, population health, and policy—transforming information abundance into actionable breakthroughs for global health.
A research paper by scientists from Liaoning Cancer Hospital & Institute, The First Affiliated Hospital of Ningbo University, and other institutions proposed a hollow mesoporous carbon (HMC) nanoparticle prepared via the sacrificial template method, featuring a porphyrin-like structure that enables efficient singlet oxygen generation and synergistic sono-immunotherapy for pancreatic cancer.
The new research paper, published on May 9 in the journal Cyborg and Bionic Systems, presented the preparation, characterization, and therapeutic application of MOF-derived HMC nanoparticles, and demonstrated their potential to enhance sono-immunotherapy efficacy by inducing tumor cell apoptosis and activating the immune
system.Mobile phones and endless screen time are the bane of parents the world over. But while technology is often blamed for poor health in children and teenagers, new University of South Australia research suggests that the same devices could also be part of the solution.
This review presents an innovative perspective on the replacement of conventional petrochemical-based surfactants with microbial biosurfactants such as rhamnolipids and sophorolipids in shampoo formulations. It emphasizes the integration of green chemistry principles and circular bioeconomy concepts into personal care product development. Unlike synthetic surfactants like SLS, biosurfactants are biodegradable, skin-compatible, and eco-friendly, reducing both dermatological irritation and environmental pollution. The article innovatively links biotechnological fermentation processes with cosmetic formulation science, providing comparative analyses of cleansing efficacy, foam stability, biodegradability, and protein protection in skin models. Moreover, it explores formulation optimization strategies, including hybrid surfactant systems and pH buffering to overcome stability and cost barriers. By combining environmental metrics with dermatological performance, this review establishes a holistic framework for sustainable shampoo design. The innovative aspect lies in positioning biosurfactants not merely as replacements for synthetics, but as multifunctional active ingredients that enhance scalp microbiome health while advancing global sustainability goals in the cosmetics industry.
With an increasing intensity and severity of heat waves in the U.S., Rutgers Health researchers, in collaboration with the City University of New York (CUNY), found that older workers, particularly Black, Latino and low-income individuals, face an increased risk of work disability because of exposure to extreme heat.