The American College of Cardiology (ACC) and OpenEvidence are entering a strategic partnership to accelerate the translation of cardiovascular clinical guidance and research into clinical implementation at the point of care. By combining ACC’s leadership in cardiovascular science and education with OpenEvidence’s advanced generative artificial intelligence (AI) technology, clinicians will have access to the latest relevant and actionable medical evidence to support shared decision-making with their patients.

Young people in Scotland are experimenting with nicotine pouches and reporting adverse effects such as sickness and fainting, according to new research from the Scottish Centre for Social Research (ScotCen) published today in the journal Addiction.

About The Study: Within the studied participants, there were clear absolute benefits of sodium-glucose cotransporter 2 (SGLT2) inhibitors on kidney, hospitalization, and mortality outcomes irrespective of diabetes status and level of urine albumin to creatinine ratio.

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented in-person at American Society of Nephrology Kidney Week 2025 November 5–9.

A new study found that a rising number of premature deaths prevent many Americans from reaching the age of Medicare eligibility. From 2012 to 2022, deaths among adults ages 18 to 64 increased by 27%, according to an analysis of federal mortality data from all 50 states.

About The Study: Between 2012 and 2022, premature mortality among adults ages 18 to 64 in the U.S. increased by over 27%. During this period, racial disparities in premature mortality widened substantially, with Black individuals experiencing persistently higher and worsening rates compared with white individuals across most states. These results raise concerns about structural inequities within the Medicare entitlement and financing system. Despite contributing to Medicare throughout their working lives, Black individuals in the U.S. are less likely to live long enough to reach the qualifying age for coverage.

About The Study: In this case series, nonoptimal temperatures were critical environmental contributors associated with mortality burden, with differential vulnerability by geographic location, cause of death, and demographic factors. These findings highlight the need for urgent actions against temperature-related health burdens through tailored climate and public health strategies, considering the local context and demographic profiles.