Medicine & Health
Updates every hour. Last Updated: 15-Aug-2025 09:10 ET (15-Aug-2025 13:10 GMT/UTC)
Study shows remotely supervised exercise can boost brain health in older adults
Shanghai Jiao Tong University Journal CenterPeer-Reviewed Publication
This study is a 6-month pilot three-arm randomised controlled trial. Eligible participants (n=108) were recruited and randomised to the AE group, RE group or control (CON) group with a 1:1:1 ratio. Interventions were delivered at home with remote supervision. We evaluated participants’ global cognition, memory, executive function, attention, physical activity levels, physical performance and muscle strength of limbs at baseline, 3 months (T1) and 6 months (T2) after randomisation. A linear mixed-effects model was adopted for data analyses after controlling for covariates. Tukey’s method was used for adjusting for multiple comparisons. Sensitivity analyses were performed after excluding individuals with low compliance rates.
- Journal
- General Psychiatry
How mental stress can break your heart
Shanghai Jiao Tong University Journal CenterIncreasing observational and experimental trial data have shown that mental stress can lead to an increase in adverse clinical cardiovascular events. Mental stress affects the heart by inducing ischaemia and precipitating myocardial infarction (MI) or direct myocardial injury. Mental stress leads to systemic inflammation. Inflammation is known to cause rapid atheromatous plaque progression, instability and thrombosis—the classic type 1 MI. Inflammation can also lead to type 2 MI or myocarditis and injury. The published data linking systemic inflammation, mental stress and cardiovascular disease will be reviewed to establish the linkage between mind and heart, thereby highlighting the importance of holistically managing the patient, not only addressing separate organ systems. Finally, recent trial evidence showing the value of anti-inflammatory drugs in cardiovascular and mental conditions will be briefly considered.
- Journal
- General Psychiatry
Cleveland Clinic research finds injectable medications for obesity produce smaller weight loss in a real-world setting, compared to randomized clinical trials
Cleveland ClinicPeer-Reviewed Publication
UNDER EMBARGO UNTIL Tuesday, June 10, 2025, 3 a.m. EDT, CLEVELAND: A Cleveland Clinic study shows that semaglutide and tirzepatide – injectable GLP-1 drugs for obesity – produce smaller weight loss in a real-world setting because patients discontinue treatment or use lower maintenance dosages. Treatment discontinuation also negatively impacted blood sugar control in patients with prediabetes. The study was published in the Obesity Journal.
- Journal
- Obesity
BEES: A new mental health tool set to create a buzz
Edith Cowan UniversityPeer-Reviewed Publication
- Journal
- Behavioral Sciences
Let’s all club together for better mental health
Flinders UniversityPeer-Reviewed Publication
Sports clubs have the potential to provide a profound and positive impact on the mental health of their younger members, but the whole club must be engaged to make a real difference.
A new study by Flinders University shows that while coaches are often the focus of mental health efforts in sport, real and sustainable change relies on recognising the role of all club stakeholders including parents, committee members, trainers and volunteers.
- Journal
- Qualitative Research in Sport Exercise and Health
- Funder
- Hospital Research Foundation, Breakthrough Mental Health Research Foundation Grant
Newly discovered cancer cell energy pathway blocked with natural substance
Osaka Metropolitan UniversityPeer-Reviewed Publication
- Journal
- Scientific Reports
- Funder
- Japan Society for the Promotion of Science