New study published in PNAS presents a blood-based proteomic signature that predicts how long people are likely to live in good health—known as healthspan. The Healthspan Proteomic Score (HPS), developed by researchers at the UConn School of Medicine and collaborators at the University of Helsinki and the University of Exeter (UK), provides a powerful tool for understanding biological aging and assessing risks for a wide range of chronic diseases.

University Hospitals Harrington Heart & Vascular Institute is expanding advanced cardiac care and vascular services in the region through the addition of a structural heart program and new cardiac catheterization laboratory at UH Lake West Medical Center.

How can additive manufacturing and metamaterials improve healthcare for aging populations? In a review published in the International Journal of Extreme Manufacturing, researchers examine how 3D printing technologies—particularly laser powder bed fusion and vat photopolymerization—are used to create personalized implants and tissue models using metals, polymers, and even living cells. Their work highlights the role of bioinspired lattice structures and mechanical metamaterials in addressing age-related biomedical challenges and advancing the future of regenerative medicine.

A team led by Rutgers University-New Brunswick engineers has developed a portable device capable of detecting rare genetic mutations from a single drop of blood.

The instrument, described in a study published in Communications Engineering of the Nature Publishing Group, was shown in lab experiments to quickly and accurately test for a genetic condition called hereditary transthyretin amyloidosis, which can cause heart problems.

Late-life mood disorders (LLMDs), such as depression and bipolar disorder, appearing after 40 years of age, may signal early neurodegenerative diseases. Using advanced PET scans and autopsy data, researchers from Japan revealed that many patients with LLMDs exhibit abnormal tau and amyloid protein accumulation—key markers of dementia—years before cognitive symptoms arise. Their findings highlight tau-PET imaging as a promising tool for detecting underlying brain pathologies, paving the way to early dementia diagnosis.