Your body's secret sugar code could predict disease years before it strikes
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Updates every hour. Last Updated: 23-Jun-2026 08:16 ET (23-Jun-2026 12:16 GMT/UTC)
Serious mental illnesses have long been sorted into separate diagnostic boxes, yet they cluster stubbornly within the same families. Researchers examined 173 multiplex families from the Portuguese Island Collection, drawn from the genetically isolated Azores and Madeira. In 28 percent of those families, psychosis and mood disorders co-segregated; in 7 percent, autism and intellectual disability joined the same pedigree. Whole-genome sequencing of one three-generation family uncovered an ultra-rare loss-of-function mutation in CHD2 that appeared as schizophrenia in most carriers and as autism in another. The work argues that founder-population families can expose rare, large-effect variants spanning the diagnostic spectrum.
A new analysis has found that after Utah lowered the legal blood alcohol concentration (BAC) limit for driving from 0.08 to 0.05 g/dL, alcohol-related crash fatalities declined significantly more in Utah compared to its six contiguous states. The findings from the study in the American Journal of Preventive Medicine, published by Elsevier, provide timely evidence that lowering the BAC limit may save lives and point to broad public safety benefits.
New grants to UC San Diego researchers will help them explain why women are more likely to get Alzheimer's disease and develop new risk-prediction tools for clinicians.
The International Society of Microbiota (ISM) is pleased to announce the appointment of Pofessor Dr. Soheil Saeedi, University Hospital Zurich and University of Zurich, Switzerland, as Vice-President of ISM.
This month’s tip sheet from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, features a variety of cancer-related story ideas, including a new immunotherapy drug that significantly extends remission and survival in relapsed multiple myeloma, paradoxical mesothelioma findings, new research illuminating how gliomas evolve after treatment, and a profile of cancer survivorship researcher.
The cost of screening people with the rare, inherited cancer-causing condition Li-Fraumeni syndrome (LFS) is roughly nine times lower than that of treatment, researchers have found. This evidence is sufficient to make the case for investing in early genetic testing in tumour risk syndromes, they say, with benefits not just for patients, but also for healthcare systems.