Biologic drug reduces symptoms, hospitalization for severe pulmonary hypertension after diagnosis
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Updates every hour. Last Updated: 4-Oct-2025 12:10 ET (4-Oct-2025 16:10 GMT/UTC)
The human brain does more than simply regulate synapses that exchange signals; individual neurons also process information through “intrinsic plasticity,” the adaptive ability to become more sensitive or less sensitive depending on context. Existing artificial intelligence semiconductors, however, have struggled to mimic this flexibility of the brain. A KAIST research team has now developed next-generation, ultra-low-power semiconductor technology that implements this ability as well, drawing significant attention.
KAIST (President Kwang Hyung Lee) announced on September 28 that a research team led by Professor Kyung Min Kim of the Department of Materials Science and Engineering developed a “Frequency Switching Neuristor” that mimics “intrinsic plasticity,” a property that allows neurons to remember past activity and autonomously adjust their response characteristics.
Supported by research from the National University of Singapore (NUS) and a strong community partnership with Lions Befrienders, Singapore’s first large-scale dance programme for pre-frail and mildly frail seniors—to be rolled out at 10 Active Ageing Centres—advances Healthier SG and Age Well SG priorities for preventive, community-based care.
A new commentary paper in Nicotine and Tobacco Research argues that recent cuts to the National Institutes of Health, including about $2 billion in terminated research grants and a $783 million cut to research funding linked to diversity and inclusion initiatives, will have a dramatically negative effect on efforts to combat tobacco usage and health disparities in the United States.
The research team led by Professors Yubo Fan and Xufeng Niu at Beihang University systematically investigated the changes in collagen fibers within atherosclerotic plaques by establishing an ApoE knockout mouse model fed with a high-fat diet, combined with histological staining, immunohistochemistry, and in vitro experiments. Their findings revealed a progressive decline in CFA orientation as AS advanced, with regions of randomization coinciding with inflammatory responses, smooth muscle cell (SMC) phenotype switching, osteogenic gene expression, and vascular calcification. These results highlight CFA as a valuable indicator for delineating lesion regions and assessing disease stages, thus providing theoretical support for early diagnosis and therapeutic intervention.