Chinese medicinal cuisine, known as yao shan, has long‑standing cultural roots in Traditional Chinese Medicine. A multi‑disciplinary Perspective puts forward a falsifiable systems‑science framework for its modernisation. Rather than simply adding modern technologies to old practices, the work converts traditional TCM concepts into testable scientific hypotheses, establishes causal research chains, separates quality‑safety‑efficacy evidence, and delivers a four‑stage roadmap to advance reproducible, internationally comparable yao‑shan research and application.

Why do some tissues regenerate efficiently after injury while others develop chronic inflammation, scar formation, or even fibrosis? A newly published review proposes that immunometabolism is not a universal "pro-inflammatory or anti-inflammatory" program but a dynamic adaptation process shaped by organ structure, regenerative capacity, injury stage, and local microenvironment. The article systematically compares six tissues—intestine, skin, liver, lung, heart, and skeletal muscle—and introduces the concept of niche-dependent immunometabolic regulation.

Researchers at Ritsumeikan University report a halogen-guided method for transforming accessible hydroxycoumarins into coumaranones, valuable heterocyclic structures in medicinal chemistry. Inspired by halogenation-driven bond cleavage in natural product biosynthesis, the method deletes a carbonyl group through simultaneous C–C and C–O bond cleavage under room temperature without the need for transition metals. The approach offers a practical strategy for molecular scaffold editing and potentially streamlining synthesis of biologically relevant compounds.

More than two-thirds of hospitalized COVID-19 survivors maintained stable cognition 2 years after Omicron infection, while one in five experienced reversible decline. Researchers report that only 10.8% developed irreversible cognitive decline, including 3.6% with progressive decline. Older age, reinfection, severe illness, hypertension, longer hospitalization, and white matter lesions increased the risk, while education and vaccination were protective. Findings highlight potential for cognitive recovery, supporting monitoring of patients at higher risk of progressive decline.