University of Cincinnati enrolls first patients in clinical trial for prosthetic joint infections
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Updates every hour. Last Updated: 22-Jun-2026 12:16 ET (22-Jun-2026 16:16 GMT/UTC)
The University of Cincinnati has enrolled the first patients in Peptilogics’ RETAIN trial, testing the effectiveness of an investigational drug in patients with prosthetic joint infections following total knee replacement.
A new Yale study reveals the distinct timing effects of maternal and paternal depression on adult mental health outcomes in the next generation, including influences on depression, anxiety, and psychotic disorders.
A research team led by Kieran O’Donnell at Yale School of Medicine (YSM) found pregnancy to be a sensitive period, with exposure to high levels of maternal depression during this time alone predictive of psychosis risk in adult offspring. This points to the importance of adequate mental health support during pregnancy, they say.
The effects of maternal depression on adult symptoms of depression were also detected across childhood, in addition to the pregnancy time period, while paternal effects emerged from mid-childhood. The findings were published online by JAMA Network Open.Researchers at Oregon Health & Science University have uncovered a key reason why immunotherapy has largely failed in pancreatic cancer — and identified a promising strategy to overcome that resistance.
The study, published in the journal Immunity, shows that pancreatic tumors actively reshape their immune environment by co‑opting regulatory immune cells that normally shut down tumor-killing cells. By reprogramming those cells, the research reveals a potential pathway to make immunotherapy effective against one of the deadliest and most treatment‑resistant cancers.
Researchers from the Institute for Systems Biology (ISB) and collaborators show that some lung cancers can change identity as they evolve, forming hybrid cell states and immune-protected regions that may help tumors evade treatment. The findings point to new opportunities for earlier detection and more precise therapies.
Today, @AmerGeriatrics names Linda Ferrie as the first ever recipient of the AGS/ADGAP Outstanding Geriatric Medicine Education Coordinator of the Year Award #AGS26 https://bit.ly/4c1MWFE
The well-being of a supervisor is reflected through supervisor-subordinate relationships in employee motivation and performance, and consequently, in the company’s competitiveness. In his doctoral research at the University of Vaasa, Finland, Project Researcher Jussi Tanskanen demonstrates that an exhausted leader lacks the resources to maintain high-quality relationships with subordinates, leading to a collapse in employee dedication. This phenomenon is particularly pronounced in today’s intensive work environment and remote work settings.
Europe’s dependence on fossil fuels is not only making the continent economically and politically vulnerable, it also has dramatic consequences for the population’s health. Growing air pollution, heat damage and the climate-related spread of infectious diseases are looming, warns the 2026 Europe Report of the Lancet Countdown on Health and Climate Change, which its co-directors Prof. Dr Joacim Rocklöv (Heidelberg University) and Prof. Dr Cathryn Tonne (Barcelona Institute for Global Health) are about to present to the public. Together with other experts from academia, practice and policy they will discuss the report’s results during a public event at Heidelberg University, comparing the current findings with successful measures for climate action and health protection. The launch event with livestreaming is to take place on 22 April 2026.