Kyoto, Japan -- Smartphones may often feel like a source of stress, feeding us an endless stream of bad news and social comparison. But what if they could also be the solution?

A team of researchers from Kyoto University believes they can be. The team has developed a smartphone app that delivers core techniques of cognitive-behavioral therapy (CBT)—a proven treatment for depression and anxiety—straight into the hands of users, and tested it in the largest-ever individually randomized trial of its kind.

Their resilience training app, called RESiLIENT, was tested on nearly 4,000 adults across Japan experiencing subthreshold depression—a form of low-level but persistent depressive symptoms that doesn’t meet criteria for major depressive disorder but can still be debilitating. This condition affects an estimated 11% of people worldwide and often goes untreated.

Singapore scientists release one of the world’s largest open-access long-read RNA sequencing datasets, paving the way for global advances in disease research and precision medicine.