Researchers at Fujita Health University and collaborators identified "hyper-maturity" in the hippocampus, excessive cellular aging, as a shared abnormality in mouse models of anxiety and other psychiatric disorders. By screening public transcriptomics datasets, they found hyper-mature signatures linked to increased anxiety. This study, published in Neuropsychopharmacology, extends beyond the authors’ previous findings on immature brain phenotypes, suggesting that both under- and over-maturation can disrupt emotional regulation, offering a new paradigm for psychiatric and aging research.

The henna tree is commonly used for making henna dye. Now, a new study suggests that the same pigments that change your skin or hair that distinctive orange-red color could be used for another purpose: treating liver disease.