Professor Philip Hyland has fundamentally transformed how the world understands trauma-related disorders through his pioneering research on Complex PTSD, which proved integral to its inclusion as a distinct diagnosis in ICD-11. His development of the International Trauma Questionnaire has become the global gold standard for trauma assessment. This Genomic Press Interview reveals how personal struggles with anxiety in his youth propelled him to revolutionize trauma psychology, ultimately improving treatment for millions worldwide.

Promoting the acceptance of clinical studies about traditional Chinese medicine (TCM) interventions by the international community is a key strategy for internationalization of TCM. However, the complexities of TCM interventions – in terms of its theories, practice patterns, and components – pose significant challenges in designing and implementing clinical studies that are well accepted by the international community. This article summarized the current status of clinical studies about TCM interventions published in international journals, explored underlying barriers to promoting their global acceptance, and discussed potential strategies for future development.

In the paper published on Science of Traditional Chinese Medicine(STCM), the authors utilized synthetic biology technology to create the first artificial herbal cell (AHC) based on a traditional Chinese medicine (TCM) formulation: Compound Danshen Yeast 1.0. This breakthrough provides foundational technology for producing TCM formulations through one-step fermentation using simple carbon sources like glucose and ethanol—eliminating the need for wild harvesting or cultivation of medicinal herbs. By harnessing synthetic biology, the team reprogrammed a single yeast strain to simultaneously synthesize three classes of active ingredients—notoginsenosides (protopanaxadiol), tanshinone diterpenoid (miltiradiene), and borneol.

Lupus patients can develop an inflammation-caused condition known as lupus nephritis, which compromises kidney function. A Medical University of South Carolina team reports in Lupus Science & Medicine that cells lining the walls of kidney blood vessels expressed genes associated with inflammation when exposed to lupus nephritis serum. However, when exposed simultaneously to the serum and the investigational drug L-sepiapterin, they instead expressed genes associated with nitric oxide production, protecting against inflammation and oxidative stress.