Researchers identify blood-based biomarker for cancer risk in people with Lynch Syndrome
Peer-Reviewed Publication
Updates every hour. Last Updated: 26-Jun-2026 04:16 ET (26-Jun-2026 08:16 GMT/UTC)
Lynch Syndrome (LS) is a hereditary condition involving mutations in DNA mismatch repair genes
Researchers sequenced T cell receptors in blood and tissue samples from LS carriers and non-carriers and characterized their T cell profiles
Study revealed unique early immune signatures in patients with LS, independent of cancer history
Blood test could serve as non-invasive tool for early cancer detection and monitoring of immune response to cancer