Clusters of metabolic dysfunction-associated steatotic liver disease for precision medicine
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-May-2025 23:09 ET (26-May-2025 03:09 GMT/UTC)
People with intellectual disabilities (ID) are significantly less likely to participate in population-based cancer screening than the general population, according to researchers from Radboudumc and academic collaborative Intellectual Disability and Health - Sterker op eigen benen in The Lancet Public Health.
A pioneering study offers unprecedented insights into the bone immune microenvironment of type 2 diabetic mice, uncovering a unique genetic profile that includes decreased osteoclast differentiation.
This newly published analysis in Genes & Diseases sheds light on the crucial role of mechanosensitive adhesion G protein-coupled receptors (aGPCRs) in regulating biological processes and their implications in various diseases. These unique receptors translate mechanical stimuli into biochemical signals, influencing cell behavior, development, and disease progression.
Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant role in ischemia/reperfusion (I/R) injury. This review sheds light on the impact of mtDNA damage on cardiac health and highlights potential therapeutic strategies.
Creation of a comprehensive genetic representation for more than 2.5 billion people across the Middle East and South Asia could make a major contribution towards advancing precision medicine.