Mount Sinai study identifies inflammatory immune pathway driving immunotherapy resistance in bladder cancer
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Updates every hour. Last Updated: 23-Jun-2026 20:16 ET (24-Jun-2026 00:16 GMT/UTC)
Groundbreaking research, led by teams at Trinity College Dublin and the FutureNeuro Research Ireland Centre, has pinpointed the mechanism linking some sports injuries to poor brain health in retired athletes.
The research, published today in leading international journal Science Translational Medicine, has identified a breakdown in the blood-brain barrier (BBB) as the key link between repetitive head injuries (RHIs) and long-term brain health issues in this cohort.
The BBB acts as a “security gate”, letting in essential nutrients while keeping harmful toxins and inflammatory cells out. But when “leaky” it cannot perform this security job properly and becomes associated with the cognitive decline and neurological damage seen in some former professional collision and combat sports athletes including rugby players and boxers.
For the first time the researchers have shown that in some retired athletes with a history of RHIs this gate remains leaky years after they have left the field.
A new editorial published in JAMA Oncology warns that cancer care progress is under threat from a "trifecta" of challenges: proposed federal budget cuts, a surge in medical misinformation, and a critical gap in public health literacy.
As World Tuberculosis Day 2026 approaches, an international group of authors describe how ending tuberculosis requires a whole-of-society approach, more effectively engaging policymakers, funding bodies and affected communities along with doctors and researchers.
A new University of Missouri study suggests mental health policies can play a significant role in how Americans choose political candidates.
A new 3D model reveals how mosquitoes adjust their flight patterns in response to visual and chemical cues. The research could help in the design of more effective traps and mosquito control strategies.