Penn Engineers have redesigned the lipid nanoparticles (LNPs) used to deliver mRNA vaccines, showing that subtle changes in lipid chemistry can influence immune cell metabolism and reduce inflammation. The findings suggest that lipid nanoparticles can actively shape how immune cells respond, opening new avenues for vaccines and immunotherapies.

A research team from the Department of Pharmacology and Pharmacy at the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) has developed an innovative AI-based cardiovascular risk prediction tool, called CardiOmicScore. With a single blood test, the system can accurately forecast the future risk of six major cardiovascular diseases (CVDs): coronary artery disease, stroke, heart failure, atrial fibrillation, peripheral artery disease and venous thromboembolism. It can also provide early warning signals up to 15 years before clinical onset. The findings were published in Nature Communications.

Medical imaging is important in healthcare; however, its overutilization can contribute to resource wastage and can cause harm to patients. While various guidelines are available for its appropriate utilization, their adoption remains a challenge. Now, a new study in Intelligent Medicine finds that domain-specific adaptation may help improve AI-assisted imaging recommendations, pointing to a new direction for value-based clinical decision support.

Australia’s new ban on social media for under-16s should be judge on much more than whether adolescents stay offline, researchers say.

Experts from Flinders University say success of the policy should be measured by its impact on young people’s mental health, school performance, digital literacy, and how they spend their time outside of social media.

Australian researchers have unlocked the possibility of creating smart wound dressings that enable real-time monitoring while also delivering healing agents in one simple, scalable platform.