China has made remarkable progress in controlling chronic hepatitis B virus (HBV) infection over the past three decades. The prevalence of hepatitis B surface antigen has declined from 9.72% in 1992 to 5.86% in 2020, with a striking reduction from 9.67% to 0.30% among children under five. Universal hepatitis B vaccination has been pivotal, preventing more than 40 million infections and seven million HBV-related deaths since 1992. Nevertheless, an estimated 75 million individuals are currently living with chronic HBV infection in China. Among them, only 59.78% are aware of their infection status, and about 30 million remain undiagnosed. Of those diagnosed, 38.25% (approximately 17 million) meet the criteria for antiviral treatment, yet only 17.33% (about three million) are receiving treatment. To accelerate progress toward the World Health Organization’s elimination targets, China has updated its clinical guidelines to expand treatment eligibility and improve diagnosis and treatment coverage. Moreover, Chinese pharmaceutical companies and academic institutions are actively engaged in developing novel therapies with promising efficacy, aiming to achieve a functional cure. China’s holistic approach, combining evidence-based public health interventions with active clinical management and innovative pharmaceutical development, provides valuable experience for global HBV elimination initiatives. This review aimed to summarize China's progress in HBV control, identify remaining gaps in diagnosis and treatment, and highlight strategic approaches, including public health interventions, clinical policy updates, and pharmaceutical innovation, toward achieving HBV elimination.

Keck Medicine of USC study reveals high doses of steroids may decrease effectiveness of certain immunotherapies for lung cancer when given before and/or during treatment.  

Today, Insilico Medicine (“Insilico”), the clinical-stage generative artificial intelligence (AI)-driven drug discovery company, announces its upcoming Summer Pharma.ai Updates webinar, scheduled for 10 a.m. ET on July 10. During the webinar, Founder and CEO Alex Zhavoronkov, PhD, will provide the latest company developments and introduce new features and applications of Insilico’s AI software suite, with a particular focus on the latest advancements in Biology42 and Chemistry42 through product demos, in-depth explanations, and real-world use cases. Ready for the future of Pharma.ai? Register here.

Researchers at the University of Tartu Institute of Genomics have gained a deeper understanding of why some people are more prone to experiencing side effects when taking antidepressants.

Researchers at the Max Planck Institute for Human Development have critically examined the basis for a frequently cited figure: that people make more than 200 unconscious decisions about food every day. This figure has circulated in scientific publications, the media, and health promotion campaigns for nearly 20 years without ever being empirically validated. An article published in the journal Appetite shows why a more nuanced view of eating behavior is needed.