Researchers from the Josep Carreras Leukaemia Research Institute and the Aragon Health Research Institute have just presented a new strategy in the fight against T-cell Acute Lymphoblastic Leukaemia. This novel therapy is based on the use of CAR-T cells designed to target two specific markers of this type of leukaemia: the CD1a and CCR9 proteins. Preclinical results of this new therapeutic approach demonstrate both high efficacy and an excellent safety profile, paving the way for clinical development in the short term.

Patients with glioblastoma (GBM)—a type of brain cancer—have a poor prognosis owing to the aggressive nature of GBM disease and limited GBM treatment options. A new study by researchers from Croatia provides critical insights into the transformative role of artificial intelligence (AI) in advancing the diagnosis and treatment of GBM. From accurately distinguishing tumor tissue in GBM to enabling personalized treatment, AI-based tools and models can revolutionize GBM treatment and care.

Scientists demonstrate how a weak handgrip can accurately correlate with numerous diseases and poor performance of daily chores among older adults

In a paper published in MedComm, embryologists and physicians in the field of reproductive medicine present evidence that DLGAP5 is proposed as a causal gene related to oocyte meiosis disorder for the first time. It expanded the current spectrum of pathogenic genes responsible for the phenotype of oocyte maturation and embryo development defects. It provided a theoretical basis and application values for clinical counseling, genetic diagnosis, and treatment strategies in infertile patients.