Non-risk-based lung cancer screening with low-dose computed tomography
National Center for Respiratory MedicinePeer-Reviewed Publication
In April 2025, the internationally renowned academic journal The Journal of the American Medical Association (JAMA) (Impact Factor: 63.5) published online a study titled “Non-Risk-Based Lung Cancer Screening With Low-Dose Computed Tomography”, led by Professors Jianxing He and Wenhua Liang from the First Affiliated Hospital of Guangzhou Medical University and the National Clinical Research Center for Respiratory Disease.
This research, focusing on lung cancer screening strategies, revealed that the non-risk-based (universal) screening approach - unrestricted by traditional high-risk criteria - achieved a comparable detection rate of lung cancer among individuals not classified as high-risk relative to those who were. The findings underscore the necessity of evaluating the effectiveness of lung cancer screening in non-high-risk populations and developing biomarker-based enrichment strategies to refine pre-screening selection in this subgroup.
- Journal
- JAMA