Using iron to destroy multiple myeloma cancer cells
Peer-Reviewed Publication
Updates every hour. Last Updated: 3-Oct-2025 20:11 ET (4-Oct-2025 00:11 GMT/UTC)
Researchers at Duke University have shown that blocking an enzyme involved in iron regulation not only kills multiple myeloma cancer cells, but also increases the effectiveness of current therapies against the disease.
Biomedical engineers at Duke University have developed a platform that combines automated wet lab techniques with artificial intelligence (AI) to design nanoparticles for drug delivery. The approach could help researchers deliver difficult-to-encapsulate therapeutics more efficiently and effectively.
Salk neuroscientists discover brain area called gracile nucleus is central to the development of mechanical allodynia, a chronic pain condition that affects 7 to 10 percent of the global population. The findings show that uncoordinated gracile nuclei neural activity patterns cause mechanical allodynia—not a simple increase in activity as previously assumed. The discovery aids the century-long scientific endeavor of deciphering how the brain perceives and encodes pain and is a crucial step toward designing acute and chronic pain therapeutics.