For infants undergoing cleft palate surgery, local anesthetic injection targeting the maxillary nerve of the face may reduce or eliminate the need for opioid medications to control postoperative pain, reports a study in The Journal of Craniofacial Surgery. The journal is published in the Lippincott portfolio by Wolters Kluwer.

A mobile health (mHealth) intervention for adolescent and young adult breast cancer survivors that offered tailored support by monitoring electronic patient-reported outcomes (ePROs) significantly improved quality of life and symptoms related to vaginal and arm problems, according to results from a randomized clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

Mass General Brigham is announcing the spinout of AIwithCare, a company founded by researchers who created a Retrieval-Augmented Generation (RAG)–based AI tool that greatly outperforms manual review in assessing patient eligibility for clinical trial enrollment. The tool, called RECTIFIER, analyzes data from electronic health records—including visit notes and clinical reports—and has the potential to expand patient access to trials and accelerate drug discovery.

Alcohol use disorder and risky alcohol drinking habits are important for primary care providers to know about and address with patients; a new study shows natural language processing, a form of artificial intelligence, could help.

Epicardial adipose tissue, the layer of fat between the heart muscle and the outer heart lining, was assessed by cardiovascular magnetic resonance in patients with acute myocardial infarction. Patients with the largest volumes of epicardial adipose tissue showed the greatest injury to the heart muscle. Prospective validation is now warranted to assess whether epicardial adipose tissue volume could be used in cardiovascular risk assessment to identify high-risk patients.