Insulin on edge: Study identifies stress-triggered gene behind diabetes
Peer-Reviewed Publication
Updates every hour. Last Updated: 12-Oct-2025 10:11 ET (12-Oct-2025 14:11 GMT/UTC)
Osaka Metropolitan University researchers identified REDD2, a stress-responsive gene that damages insulin-producing pancreatic β-cells under metabolic stress. By disrupting insulin secretion, REDD2 contributes to the onset of type 2 diabetes. Suppressing this gene in mice helped preserve β-cell function and improve glucose control, offering a potential target for early diabetes intervention.
Stanford's Eric Sun has created sophisticated machine learning frameworks that measure biological aging at single-cell resolution, discovering cell types that can dramatically accelerate or slow aging in surrounding brain tissue. His recent Nature publication establishes new computational tools for understanding brain aging and developing targeted interventions against age-related cognitive decline.
In this April 2025 issue of Annals of Thoracic Surgery (JCR Q1, IF: 3.6), a retrospective study, led by Professors Jianxing He and Shuben Li from the First Affiliated Hospital of Guangzhou Medical University, illustrated the safety, feasibility, and efficacy of extended sleeve lobectomy (ESL) after neoadjuvant immunochemotherapy in patients with centrally located non-small cell lung cancer (NSCLC).
The article entitled "Extended Sleeve Lobectomy After Neoadjuvant Immunochemotherapy for Centrally Located Non-small Cell Lung Cancer". It is the first study to evaluate the impact of neoadjuvant immunochemotherapy on ESL. The results demonstrated that ESL after neoadjuvant immunochemotherapy is a viable and safe option for selected patients with centrally located NSCLC to avoid pneumonectomy(PN), especially when standard sleeve lobectomy (SSL) is insufficient for R0 resection.
The military prides itself on loyalty and respect but those values must extend to how they treat those who leave service.
A new study analysed responses from nearly 400 former Australian Defence Force (ADF) members, uncovering widespread dissatisfaction with their discharge including reporting overt abuses of power and objectively harmful actions, such as finding their belongings packed up and removed from base and being marched off base without notice or means of travel.
The military prides itself on loyalty and respect but those values must extend to how they treat those who leave service.
A new study analysed responses from nearly 400 former Australian Defence Force (ADF) members, uncovering widespread dissatisfaction with their discharge including reporting overt abuses of power and objectively harmful actions, such as finding their belongings packed up and removed from base and being marched off base without notice or means of travel.